What is one beneficial effect of weight loss on glucose regulation?

Weight loss has a significant beneficial effect on glucose regulation, primarily through its ability to improve insulin sensitivity. When a person reduces their body weight, particularly if the weight loss is achieved through healthy lifestyle changes like diet and exercise, the body's cells become more responsive to insulin. Insulin is a hormone that helps regulate blood sugar levels by facilitating the uptake of glucose into the cells. When insulin sensitivity improves, the body requires less insulin to process glucose, which can lead to better blood sugar control.

This effect is particularly important for individuals who are overweight or obese, as excess body fat—especially abdominal fat—can contribute to the development of insulin resistance, a condition where the body's cells do not respond effectively to insulin. Improved insulin sensitivity not only helps to stabilize blood glucose levels but also reduces the risk of developing type 2 diabetes and other associated metabolic conditions.

In contrast, the other choices describe negative or neutral effects that do not align with the beneficial outcomes of weight loss on glucose regulation. Such understanding highlights the importance of maintaining a healthy weight for metabolic health.