Thyroid-stimulating hormone is secreted by which gland to stimulate the production of T4?

Thyroid-stimulating hormone (TSH) is secreted by the anterior pituitary gland. Its primary role is to stimulate the thyroid gland to produce and release thyroid hormones, primarily thyroxine (T4) and triiodothyronine (T3). When the levels of thyroid hormones in the bloodstream decrease, the anterior pituitary is triggered to release TSH. This increases the activity of the thyroid gland, leading to the synthesis and secretion of T4 and T3, which in turn help regulate metabolism, energy levels, and overall growth and development.

Other glands such as the adrenal gland, thyroid gland itself, or pancreas do not produce TSH. The adrenal gland is involved in producing hormones like cortisol and adrenaline, the thyroid gland produces T4 and T3 but does not secrete TSH, and the pancreas primarily regulates glucose metabolism through insulin and glucagon. Therefore, the role of TSH and its origin from the anterior pituitary is crucial for maintaining proper thyroid function and overall metabolic balance.